Head of the Computer-Aided Drug Design Unit (CADD)
Email: daadoosh@tauex.tau.ac.il
Dr. Benny Da'adoosh joined the BCDD after finishing his Ph.D. at HUJI (School of Pharmacy, Faculty of Medicine) in 2017, under the supervision of Prof. Amiram Goldblum. His research focused on developing computational methods for finding substrate-selective inhibitors of enzymes, as well as discovering novel agonists of a nuclear receptor (PPAR-delta) in collaboration with the Genomics Institute of Novartis Research (San Diego).
Dr. Benny Da'adoosh specializes in the computerization of medicinal chemistry and structural biology, encompassing the management and analysis of small molecule datasets, methods for predicting interactions between small molecules and proteins (such as docking and pharmacophore), protein structure modeling, and SAR analysis. He is proficient in various programming languages, including Python, Perl, C++, MATLAB, and more, as well as a range of computational tools for chemoinformatics (RDkit, OpenBabel), virtual screening (Glide, FlexX, LigandScout, Phase, Prime), homology modeling (Prime), molecular dynamics (Desmond, Gromacs, Amber), SAR (SeeSAR), scaffold hopping (InfiniSee), and others.
Since joining the BCDD in 2017, Dr. Benny Da'adoosh has been involved in the computational aspects of drug discovery and design, as well as providing guidance to medicinal chemists on SAR and computational aspects. His work has contributed to securing grants and publishing peer-reviewed papers.
